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cardiometabolic riskdiabetes proamerican diabetes association

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1、-Insert HereSpeaker Titleand AffiliationA comprehensive approach to patient care; Multiple disease pathways and risk factors are considered to facilitate earlier interventionEarly assessment and targeted intervention are needed to treat and prevent all risk factors associated with CVD and diabetes G

2、ives a comprehensive picture of a patients health and potential risk for future disease and complicationsIs inclusive of all risks related to metabolic changes associated with CVDAccommodates emerging risk factors as useful predictive toolsFocuses clinical attention to the value of systematic evalua

3、tion, education, disease prevention and treatmentSupports an integrated approach to careKahn, et al. The Metabolic Syndrome: Time for a Critical Appraisal: Joint Statement From the AmericanDiabetes Association and the European Association for the Study of Diabetes Diabetes Care. 2005;28 (9)2289-2304

4、. 2 out of 3 Americans are overweight or obese More than 70 million (nearly 1 in 4) Americans have varying degrees of insulin resistance There are an estimated 54 million (more than 1 in 6) Americans with prediabetes Nearly 1 in 4 U.S. adults has high cholesterol 1 in 3 American adults has high bloo

5、d pressure$296 billion$152 billion$116 billion$58 billion$412 billion$210 billion*Note: these figures may not account for potential overlap.Sources: 2008 statistics from the American Diabetes Association and American Heart Association.CardiovascularDiseaseDiabetesTOTALEstimated DirectMedical CostsEs

6、timated Indirect Costs(disability, work loss, premature mortality)Abnormal Lipid MetabolismLDL ApoB HDL Trigly. Cardiometabolic RiskGlobal Diabetes / CVD RiskOverweight / ObesityInflammation HypercoagulationHypertensionSmokingPhysical InactivityUnhealthy EatingAge, Race, Gender, Family History Gluco

7、se BP LipidsAgeGeneticsInsulin Resistance?AgeRace/ethnicityGenderFamily historyOverweightAbnormal lipid metabolismInflammation, hypercoagulationHypertensionSmokingPhysical inactivityUnhealthy dietInsulin resistance 47-year-old African American man, hasnt seen doctor in years Works as a truck driver,

8、 eats mostly fast food Smokes 1 pack per day At health fair found to have BP = 146/86, total cholesterol = 210 Weight = 230 lbs; BMI = 29 kg/m Family history of HTN and diabetesAge47Race/ethnicityAfrican AmericanGenderMaleFamily historyHTN and diabetesOverweight/obesityBMI = 29Abnormal lipid metab T

9、C = 210HypertensionBP = 146/86Smoking1 pack per dayPhysical InactivityYesUnhealthy dietFast food dietNumberCenters for Disease Control and Prevention. National diabetes fact sheet: general information and nationalestimates on diabetes in the United States, 2005. Atlanta, GA: U.S. Department of Healt

10、h and Human Services,Centers for Disease Control and Prevention, 2005.800,000600,000400,000200,0000Age Group20-3940-5960+Centers for Disease Control & Prevention, Division for Heart Disease andStroke Prevention, Addressing the Nations Leading Killers: At A Glance 2007 DiagnosedDiabetesSmokingHigh Bl

11、oodPressureHigh TotalCholesterol1960-19621971-19751976-19801988-19941999-2000Centers for Disease Control and Prevention. National diabetes fact sheet: general information and nationalestimates on diabetes in the United States, 2005. Atlanta, GA: U.S. Department of Health and Human Services,Centers f


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